Our first focused product: a silk-based screw and plate system designed to stabilise fractures, then safely resorb as bone heals — eliminating the second surgery of metal hardware.
Permanent metal implants can require removal surgery and may shield bone from natural loading. SilkMatrix Osteo™ is designed to provide fixation strength during healing and then resorb into benign protein by-products.
During his graduate research at IIT Kanpur, the founder demonstrated that a silk-fibroin cryogel can meet bone-fixation requirements. That research established feasibility and capability — the springboard for SilkMatrix, which develops its own modern, clinical-grade device and IP.
Cryogel constructs engineered with compressive strength comparable to human bone and porosity like cancellous bone.
Validated via SEM, mechanical testing and cytocompatibility evaluation.
Shown feasible as a bioresorbable orthopaedic implant with tunable mechanics.
The program advances through a disciplined sequence of verification — each stage gated before the next is committed.
Establish consistent, medical-grade silk biomaterial with defined strength and resorption.
Design the screw / plate geometry and verify mechanical performance against fixation requirements.
Structured biological-safety testing of the finished material and device.
Early in-vivo safety and resorption behaviour in small-animal models.
Functional fixation performance in clinically relevant large-animal models.
Prepare for scaled manufacturing, quality systems, and the clinical / regulatory phase.
Investment is deployed against evidence. Each phase concludes with an explicit Go / No-Go before the next is committed.
Reproducibility, formulation, early safety, and IP / legal readiness.
Develop the screw / plate system, verify mechanics, and complete biological & animal validation.
Detailed work packages, budgets, and milestones are shared under confidentiality with qualified investors and advisors.